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The Buffalo Bills have been on a dominant tear in recent weeks, and there’s little to suggest they’ll slow down now. The San Francisco 49ers, meanwhile, are reeling from a wave of injuries that have derailed their season. After starting the year without Christian McCaffrey, he returned just in time for Brock Purdy, Nick Bosa, and Trent Williams to land on the injury list. Even McCaffrey hasn’t looked like his former All-Pro self, failing to surpass 100 rushing yards in any game this season and going three straight games without a touchdown. Meanwhile, Brandon Allen's performance last week against the Packers was uninspiring, as the 49ers managed just 10 points. Nick Bosa is a game-changing edge rusher, and Trent Williams might be the most impactful non-quarterback in the NFL, but their absence or limitations will leave the 49ers vulnerable. The Bills’ defense is poised to pressure either Allen or Purdy, especially with Williams sidelined or less than 100%. Buffalo has won its last five games by at least a touchdown, and in prime time, they’re a strong bet to cover again. Take Buffalo ATS


NFL Football Picks
Sunday, December 1st 2024 8:20 PM
Finished

NFL Football Cappers Picks for San Francisco 49ers vs Buffalo Bills with Cappers winnings percentage over 55% for the last 7 days:


John Rainey 86 % Double Dragon 54 % Stephen Nover 83 % Liev Jackson 67 % Duck Investments 75 % Chris Jordan 75 % R.J. White 100 % HEdge Admin 57 % James Kaylor 75 % Bender Wins 71 % Lenny Stevens 100 % Jim Feist 56 % James Salinas 57 % Dquan Picks 75 % The Champ 65 % Ashley Olsen 57 % The Sharp 56 % Tommy G 71 %

Spread
Money
Total
6.5 -112
248
O45.5 -110
-6.5 -108
-302
U45.5 -110


SPREAD
San Francisco 49ers 6.5 (-112)
AVG SPREAD W%: 50 ROI: -4
Jackson Reyes W%: 56 ROI: 8 Weston Stradtman W%: 55 ROI: 4 Chris Macero W%: 50 ROI: -5 James Salinas W%: 44 ROI: -16 Scott Pritchard W%: 48 ROI: -8 Randy McKay W%: 49 ROI: -7 Steve Fezzik W%: 54 ROI: -1 Josh Schonwald W%: 49 ROI: -5 Trent Pruitt W%: 50 ROI: -4 Ryan Dodson W%: 49 ROI: -4 Wayne Root W%: 46 ROI: -12 Bender Wins W%: 50 ROI: -9 Lenny Stevens W%: 49 ROI: -7 The Sharp W%: 55 ROI: 6 Bryan Power W%: 49 ROI: -7

SPREAD
Buffalo Bills -6.5 (-108)
AVG SPREAD W%: 50 ROI: -5
Chris Jordan W%: 46 ROI: -10 Jason La Canfora W%: 47 ROI: -9 Pete Prisco W%: 48 ROI: -9 Will Brinson W%: 45 ROI: -14 Z Code System W%: 49 ROI: -5 Micah Roberts W%: 49 ROI: -8 Double Dragon W%: 51 ROI: -4 Chris Ruffolo W%: 50 ROI: -6 Jake Allmann W%: 49 ROI: -7 Paul Biagioli W%: 51 ROI: -2 Shane Mickle W%: 50 ROI: -5 Chris Farley W%: 55 ROI: 5 Final Score Network W%: 56 ROI: 5 Brad Feinberg W%: 46 ROI: -12 Raphael Esparza W%: 48 ROI: -8 Ashley Olsen W%: 50 ROI: -5 Sean Higgs W%: 45 ROI: -14 Jesse Schule W%: 50 ROI: -11 Bob Bafle W%: 51 ROI: -3 Northcoast Sports W%: 49 ROI: -6 Jim Feist W%: 47 ROI: -12 Dquan Picks W%: 51 ROI: -9 The Champ W%: 51 ROI: -7 John Rainey W%: 47 ROI: -10 Liev Jackson W%: 46 ROI: -10 Duck Investments W%: 55 ROI: -4 Adam Silverstein W%: 55 ROI: 4 R.J. White W%: 50 ROI: -5 HEdge Admin W%: 66 ROI: 25 James Kaylor W%: 51 ROI: -5



MONEY
San Francisco 49ers 248
AVG MONEY W%: 49 ROI: -4
Ryan Dodson W%: 49 ROI: -4

MONEY
Buffalo Bills -302
AVG MONEY W%: 51 ROI: -8
Tommy G W%: 51 ROI: -8

TOTAL
UNDER 45.5 (-110)
AVG UNDER W%: 49 ROI: -6
Chris Ruffolo W%: 50 ROI: -6 Trent Pruitt W%: 50 ROI: -4 Chris Farley W%: 55 ROI: 5 Mike Tierney W%: 50 ROI: -4 Ryan Dodson W%: 49 ROI: -4 Porter Picks W%: 50 ROI: -6 LVSB Total W%: 47 ROI: -11 Stephen Nover W%: 49 ROI: -7 Daniel Vithlani W%: 45 ROI: -16

TOTAL
OVER 45.5 (-110)
AVG OVER W%: 49 ROI: -5
Z Code System W%: 49 ROI: -5 Scott Pritchard W%: 48 ROI: -8 Steve Fezzik W%: 54 ROI: -1 Timothy Earle W%: 46 ROI: -10 Dimers W%: 47 ROI: -6 Bob Bafle W%: 51 ROI: -3