MLB Baseball Bets 2025-05-21

MLB Baseball Odds & Lines

Spread

Money

Total

May 21-12:35 PM

Cincinnati Reds

-1.5 135

-125

O8.0 -105

Pittsburgh Pirates

1.5 -155

114

U8.0 -115

FirstFiveInnings

Cincinnati Reds

-0.5 115

-120

O4.0 -125

Pittsburgh Pirates

0.5 -135

-100

U4.0 102

FirstInning

Cincinnati Reds

-

-115

O1.5 260

Pittsburgh Pirates

-

-115

U1.5 -370

May 21-1:10 PM

-1.5 112

-145

O9.0 -110

1.5 -132

130

U9.0 -110

FirstFiveInnings

Chicago Cubs

-0.5 105

-135

O5.0 110

Miami Marlins

0.5 -125

115

U5.0 -130

FirstInning

Chicago Cubs

-

-115

O1.5 200

Miami Marlins

-

-115

U1.5 -275

May 21-1:10 PM

Baltimore Orioles

1.5 -195

108

O8.0 -112

Milwaukee Brewers

-1.5 168

-118

U8.0 -107

FirstFiveInnings

Baltimore Orioles

0.5 -140

-100

O4.5 -105

Milwaukee Brewers

-0.5 120

-120

U4.5 -115

FirstInning

Baltimore Orioles

-

105

O1.5 220

Milwaukee Brewers

-

-135

U1.5 -300

May 21-1:10 PM

Cleveland Guardians

1.5 -174

147

O7.5 -114

Minnesota Twins

-1.5 147

-159

U7.5 -110

FirstFiveInnings

Cleveland Guardians

0.5 -145

-105

O4.0 -105

Minnesota Twins

-0.5 125

-115

U4.0 -115

FirstInning

Cleveland Guardians

-

-100

O1.5 265

Minnesota Twins

-

-130

U1.5 -380

May 21-1:10 PM

-1.5 110

-144

O8.5 -110

1.5 -130

130

U8.5 -110

FirstFiveInnings

Houston Astros

-0.5 -110

-150

O4.5 110

Tampa Bay Rays

0.5 -110

130

U4.5 -130

FirstInning

Houston Astros

-

-135

O1.5 210

Tampa Bay Rays

-

105

U1.5 -290

May 21-1:15 PM

1.5 -200

102

O8.5 -115

St. Louis Cardinals

-1.5 170

-112

U8.5 -105

FirstFiveInnings

Detroit Tigers

0.5 -140

-100

O4.5 -115

St. Louis Cardinals

-0.5 120

-120

U4.5 -105

FirstInning

Detroit Tigers

-

-110

O1.5 200

St. Louis Cardinals

-

-120

U1.5 -275

May 21-2:10 PM

Seattle Mariners

-1.5 120

-139

O8.5 -110

Chicago White Sox

1.5 -140

124

U8.5 -110

FirstFiveInnings

Seattle Mariners

-0.5 130

-110

O4.5 -105

Chicago White Sox

0.5 -150

-107

U4.5 -115

FirstInning

Seattle Mariners

-

-120

O1.5 235

Chicago White Sox

-

-110

U1.5 -330

May 21-3:45 PM

Kansas City Royals

1.5 -120

180

O7.5 105

San Francisco Giants

-1.5 -100

-205

U7.5 -125

FirstFiveInnings

Kansas City Royals

0.5 115

170

O4.0 105

San Francisco Giants

-0.5 -135

-200

U4.0 -125

FirstInning

Kansas City Royals

-

135

O1.5 275

San Francisco Giants

-

-180

U1.5 -400

May 21-6:45 PM

-1.5 105

-147

O8.5 -110

Washington Nationals

1.5 -125

132

U8.5 -110

FirstFiveInnings

Atlanta Braves

-0.5 -105

-145

O4.5 -105

Washington Nationals

0.5 -115

125

U4.5 -112

FirstInning

Atlanta Braves

-

-125

O1.5 220

Washington Nationals

-

-105

U1.5 -300

May 21-6:45 PM

1.5 -164

128

O8.0 -105

-1.5 144

-140

U8.0 -115

FirstFiveInnings

New York Mets

0.5 -105

129

O4.0 -110

Boston Red Sox

-0.5 -115

-155

U4.0 -110

FirstInning

New York Mets

-

110

O1.5 275

Boston Red Sox

-

-145

U1.5 -400

May 21-7:00 PM

San Diego Padres

1.5 -150

141

O8.5 -120

Toronto Blue Jays

-1.5 130

-156

U8.5 -100

FirstFiveInnings

San Diego Padres

0.5 -100

145

O5.0 -100

Toronto Blue Jays

-0.5 -120

-169

U5.0 -120

FirstInning

San Diego Padres

-

115

O1.5 200

Toronto Blue Jays

-

-150

U1.5 -275

May 21-7:05 PM

1.5 -220

104

O7.5 -115

New York Yankees

-1.5 180

-114

U7.5 -105

FirstFiveInnings

Texas Rangers

-0.5 105

-132

O4.0 -105

New York Yankees

0.5 -125

115

U4.0 -115

FirstInning

Texas Rangers

-

-115

O1.5 265

New York Yankees

-

-115

U1.5 -380

May 21-8:40 PM

Philadelphia Phillies

-1.5 -140

-206

O11.5 -105

Colorado Rockies

1.5 120

180

U11.5 -115

FirstFiveInnings

Philadelphia Phillies

-0.5 -120

-160

O6.0 -115

Colorado Rockies

0.5 -100

140

U6.0 -105

FirstInning

Philadelphia Phillies

-

-170

O1.5 140

Colorado Rockies

-

130

U1.5 -190

May 21-10:05 PM

Los Angeles Angels

1.5 -135

149

O10.5 -115

-1.5 115

-166

U10.5 -105

FirstFiveInnings

Los Angeles Angels

0.5 -105

135

O6.0 -105

Athletics

-0.5 -115

-155

U6.0 -115

FirstInning

Los Angeles Angels

-

120

O1.5 150

Athletics

-

-160

U1.5 -210

May 21-10:10 PM

Arizona Diamondbacks

1.5 -165

126

O9.0 -115

Los Angeles Dodgers

-1.5 140

-140

U9.0 -105

FirstFiveInnings

Arizona Diamondbacks

0.5 -125

108

O5.0 -100

Los Angeles Dodgers

-0.5 105

-130

U5.0 -120

FirstInning

Arizona Diamondbacks

-

110

O1.5 210

Los Angeles Dodgers

-

-145

U1.5 -290